Stanley Kubrick was pretty powerful, but his Napoleon film was canceled for budget reasons.
Ridley Scott wanted to direct an Alien sequel written by James Cameron, but it was canceled so 20th Century Fox could make a bunch of Alien vs. Predator movies. That sounds insane, but it really happened.
Robert Zemeckis was never as powerful, but he had cartoon hits with The Polar Express, Beowulf and A Christmas Carol. Disney canceled his remake of Yellow Submarine anyway.
I don't think it's ever happened, but theoretically, Bertolucci could get canceled.